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TMPRSS3 Antibody (aa420-460)

Rabbit Polyclonal Antibody

     
  • WB - TMPRSS3 Antibody (aa420-460) ALS16248
    Western blot of TMPRSS3 (F440) pAb in extracts from HUVEC cells.
  • IHC - TMPRSS3 Antibody (aa420-460) ALS16248
    Anti-TMPRSS3 antibody IHC staining of human uterus.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession P57727
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 49kDa
Dilution IF (1:50-1:200), IHC-P (1:100), WB (1:500-1:1000)
Additional Information
Gene ID 64699
Other Names Transmembrane protease serine 3, 3.4.21.-, Serine protease TADG-12, Tumor-associated differentially-expressed gene 12 protein, TMPRSS3, ECHOS1, TADG12
Target/Specificity Human TMPRSS3
Reconstitution & Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PrecautionsTMPRSS3 Antibody (aa420-460) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMPRSS3
Synonyms ECHOS1, TADG12
Function Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro).
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein
Tissue Location Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas
Research Areas
Citations (0)

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Background

Probable serine protease that play a role in hearing. Acts as a permissive factor for cochlear hair cells survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro).

References

Underwood L.J.,et al.Biochim. Biophys. Acta 1502:337-350(2000).
Scott H.S.,et al.Nat. Genet. 27:59-63(2001).
Ahmed Z.M.,et al.BMC Med. Genet. 5:24-24(2004).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS16248
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