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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ARG2 / Arginase 2 Antibody (aa180-348)   

ARG2 / Arginase 2 Antibody (aa180-348)

Rabbit Polyclonal Antibody

     
  • WB - ARG2 / Arginase 2 Antibody (aa180-348) ALS16253
    0
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P78540
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 39kDa
Dilution ELISA (1:20000-1:80000), IHC-P (10 µg/ml), WB (1:1000-1:2000)
Additional Information
Gene ID 384
Other Names Arginase-2, mitochondrial, 3.5.3.1, Kidney-type arginase, Non-hepatic arginase, Type II arginase, ARG2
Target/Specificity Human Arginase II / ARG2.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsARG2 / Arginase 2 Antibody (aa180-348) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARG2
Function May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
Cellular Location Mitochondrion.
Tissue Location Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas
Volume 50 µl
Research Areas
Citations (0)

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Background

May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.

References

Gotoh T.,et al.FEBS Lett. 395:119-122(1996).
Vockley J.G.,et al.Genomics 38:118-123(1996).
Morris S.M. Jr.,et al.Gene 193:157-161(1997).
Lee Y.T.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS16253
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