|Application ||WB, IHC-P, IF, IP|
|Dilution||IF (1:100), IHC-P (10 µg/ml), WB (1:2000)|
|Other Names||Low affinity immunoglobulin gamma Fc region receptor II-a, IgG Fc receptor II-a, CDw32, Fc-gamma RII-a, Fc-gamma-RIIa, FcRII-a, CD32, FCGR2A, CD32, FCG2, FCGR2A1, IGFR2|
|Target/Specificity||Human CD32A / CD32|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||CD32A Antibody (clone 13D7) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CD32, FCG2, FCGR2A1, IGFR2|
|Function||Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Found on monocytes, neutrophils and eosinophil platelets|
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Provided below are standard protocols that you may find useful for product applications.
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Stuart S.G.,et al.J. Exp. Med. 166:1668-1684(1987).
Brooks D.G.,et al.J. Exp. Med. 170:1369-1385(1989).
Gregory S.G.,et al.Nature 441:315-321(2006).
Hibbs M.L.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:2240-2244(1988).
Stengelin S.,et al.EMBO J. 7:1053-1059(1988).
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