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CD20 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • IHC - CD20 Antibody (C-Terminus) ALS16274
    Anti-CD20 antibody IHC staining of human tonsil.
    detail
  • IHC - CD20 Antibody (C-Terminus) ALS16274
    Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
    detail
  • WB - CD20 Antibody (C-Terminus) ALS16274
    Staining (4µg/ml) of Daudi lysate (RIPA buffer, 20µg total protein per lane).
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P11836
Host Goat
Clonality Polyclonal
Calculated MW 33kDa
Dilution IHC-P (2-2.5 µg/ml), WB (3-5 µg/ml),
Additional Information
Gene ID 931
Other Names B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20, MS4A1, CD20
Target/Specificity Human CD20 / MS4A1
Reconstitution & Storage Store vial at -20 C or below prior to opening. For extended storage, aliquot contents and freeze at -20 C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
PrecautionsCD20 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MS4A1
Synonyms CD20
Function B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111). Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed:7684739, PubMed:12920111, PubMed:18474602).
Cellular Location Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor. Note=Constitutively associated with membrane rafts.
Tissue Location Expressed on B-cells.
Research Areas
Citations (0)
citation

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Background

This protein may be involved in the regulation of B-cell activation and proliferation.

References

Stamenkovic I.,et al.J. Exp. Med. 167:1975-1980(1988).
Tedder T.F.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:208-212(1988).
Einfeld D.A.,et al.EMBO J. 7:711-717(1988).
Tedder T.F.,et al.J. Immunol. 142:2560-2568(1989).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 467.50
Cat# ALS16274
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