|Application ||WB, IHC-P, IF, IP|
|Dilution||IF (1:100-1:1000), IHC-P (1:100), IP (2-5 µg/mg lysate), WB (1:2000-1:10000) ,|
|Other Names||Coronin-1B, Coronin-2, CORO1B|
|Target/Specificity||Region between residue 450 and 489 of human Coronin, actin binding protein, 1B using the numbering given in entry NP_065174.1 (GeneID 57175).|
|Reconstitution & Storage||Store at 2-8°C for up to 1 year.|
|Precautions||CORO1B Antibody (aa450-489) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Note=Localized to the leading edge in fibroblasts, as well as weakly along actin stress fibers|
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Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Cai L.,et al.J. Biol. Chem. 280:31913-31923(2005).
Olsen J.V.,et al.Sci. Signal. 3:RA3-RA3(2010).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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