|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:64000), IHC-P (5 µg/ml), WB (0.5-2 µg/ml)|
|Other Names||Leukocyte elastase inhibitor, LEI, Monocyte/neutrophil elastase inhibitor, EI, M/NEI, Peptidase inhibitor 2, PI-2, Serpin B1, SERPINB1, ELANH2, MNEI, PI2|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||SERPINB1 Antibody (aa130-143) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ELANH2, MNEI, PI2|
|Function||Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also functions as a potent intracellular inhibitor of granzyme H.|
|Cellular Location||Cytoplasm. Cytoplasmic granule|
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Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also functions as a potent intracellular inhibitor of granzyme H.
Remold-O'Donnell E.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:5635-5639(1992).
Zeng W.,et al.Gene 213:179-187(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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