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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   SPAG9 Antibody (aa1-50)   

SPAG9 Antibody (aa1-50)

Rabbit Polyclonal Antibody

     
  • WB - SPAG9 Antibody (aa1-50) ALS16322
    Detection of Mouse and Rat JLP by Western Blot.
  • IHC - SPAG9 Antibody (aa1-50) ALS16322
    Anti-SPAG9 antibody IHC staining of human testis.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession O60271
Reactivity Human, Mouse, Rat, Pig, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 146kDa
Dilution IF (1:500-1:2500), IHC-P (5 µg/ml), WB (1:1000-1:10000)
Additional Information
Gene ID 9043
Other Names C-Jun-amino-terminal kinase-interacting protein 4, JIP-4, JNK-interacting protein 4, Cancer/testis antigen 89, CT89, Human lung cancer oncogene 6 protein, HLC-6, JNK-associated leucine-zipper protein, JLP, Mitogen-activated protein kinase 8-interacting protein 4, Proliferation-inducing protein 6, Protein highly expressed in testis, PHET, Sperm surface protein, Sperm-associated antigen 9, Sperm-specific protein, Sunday driver 1, SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Target/Specificity Region between residue 1 and 50 of human JNK/SAPKAssociated Protein using the numbering given in entry NP_003962.3 (GeneID 9043).
Reconstitution & Storage Store at 2-8°C for up to 1 year.
PrecautionsSPAG9 Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPAG9
Synonyms HSS, KIAA0516, MAPK8IP4, SYD1
Function The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Isoform 5 may play a role in spermatozoa-egg- interaction.
Cellular Location Cytoplasm. Cytoplasm, perinuclear region. Note=Perinuclear distribution in response to stress signals such as UV radiation
Tissue Location Isoform 5 is expressed only in testis on the round spermatids of stage I, II and II. Isoform 5 is absent in spermatogonia and spermatocyte. Isoform 3 is expressed in testis Isoform 4 is expressed in testis and in acute myeloid leukemia (AML) patients.
Volume 50 µl
Research Areas
Citations (0)

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Background

The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Isoform 5 may play a role in spermatozoa-egg- interaction.

References

Lee C.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:14189-14194(2002).
Guinn B.-A.,et al.Biochem. Biophys. Res. Commun. 335:1293-1304(2005).
Nagase T.,et al.DNA Res. 5:31-39(1998).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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Discontinued
Cat# ALS16322
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