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Acetyl-CoA Carboxylase / ACC Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - Acetyl-CoA Carboxylase / ACC Antibody (C-Terminus) ALS16328
    Anti-Acetyl-CoA Carboxylase / ACC antibody IHC staining of human brain, cortex.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q13085
Reactivity Human, Mouse, Rat, Rabbit, Sheep, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 266kDa
Dilution IHC-P (5 µg/ml), WB (1:2000-1:10000),
Additional Information
Gene ID 31
Other Names Acetyl-CoA carboxylase 1, ACC1, 6.4.1.2, ACC-alpha, Biotin carboxylase, 6.3.4.14, ACACA, ACAC, ACC1, ACCA
Target/Specificity Region between residue 2333 and the C-terminus (residue 2383) of human acetyl-Coenzyme A carboxylase alpha using the numbering given in entry NP_942131.1 (GeneID 31).
Reconstitution & Storage Store at 2-8°C for up to 1 year.
PrecautionsAcetyl-CoA Carboxylase / ACC Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACACA
Synonyms ACAC, ACC1, ACCA
Function Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
Cellular Location Cytoplasm.
Tissue Location Expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver
Volume 50 µl
Research Areas
Citations (0)

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Background

Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.

References

Abu-Elheiga L.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:4011-4015(1995).
Mao J.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:7515-7520(2003).
Sinilnikova O.M.,et al.Carcinogenesis 25:2417-2424(2004).
Travers M.T.,et al.Biochim. Biophys. Acta 1634:97-106(2003).
Travers M.T.,et al.Genomics 85:71-84(2005).

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Discontinued
Cat# ALS16328
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