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MYOF / Myoferlin Antibody (aa700-750)

Rabbit Polyclonal Antibody

     
  • WB - MYOF / Myoferlin Antibody (aa700-750) ALS16329
    Detection of Human Myoferlin by Western Blot.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IP
Primary Accession Q9NZM1
Reactivity Human, Mouse, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 235kDa
Dilution IHC-P (5 µg/ml), IP (2-10 µg/mg lysate), WB (1:1000-1:5000)
Additional Information
Gene ID 26509
Other Names Myoferlin, Fer-1-like protein 3, MYOF, FER1L3, KIAA1207
Target/Specificity Region between residue 700 to 750 of human Myoferlin using the numbering given in entry NP_038479.1 (GeneID 26509).
Reconstitution & Storage Store at 2-8°C for up to 1 year.
PrecautionsMYOF / Myoferlin Antibody (aa700-750) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYOF
Synonyms FER1L3, KIAA1207
Function Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Involved in endocytic recycling. Implicated in VEGF signal transduction by regulating the levels of the receptor KDR (By similarity).
Cellular Location Cell membrane; Single-pass type II membrane protein. Nucleus membrane; Single-pass type II membrane protein Cytoplasmic vesicle membrane; Single-pass type II membrane protein. Note=Concentrated at the membrane sites of both myoblast- myoblast and myoblast-myotube fusions. Detected at the plasmalemma in endothelial cells lining intact blood vessels (By similarity) Found at nuclear and plasma membranes. Enriched in undifferentiated myoblasts near the plasma membrane in puncate structures.
Tissue Location Expressed in myoblast and endothelial cells (at protein level). Highly expressed in cardiac and skeletal muscles. Also present in lung, and at very low levels in kidney, placenta and brain.
Volume 50 µl
Research Areas
Citations (0)

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Background

Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Involved in endocytic recycling. Implicated in VEGF signal transduction by regulating the levels of the receptor KDR (By similarity).

References

Davis D.B.,et al.Hum. Mol. Genet. 9:217-226(2000).
Britton S.,et al.Genomics 68:313-321(2000).
Nagase T.,et al.DNA Res. 6:337-345(1999).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Deloukas P.,et al.Nature 429:375-381(2004).

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Discontinued
Cat# ALS16329
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