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E2F5 Antibody (aa93-142)

Rabbit Polyclonal Antibody

     
  • WB - E2F5 Antibody (aa93-142) ALS16341
    Western blot of E2F-5 antibody in extracts from HeLa cells.
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  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q15329
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 38kDa
Dilution ELISA (1:10000), IHC-P (20 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 1875
Other Names Transcription factor E2F5, E2F-5, E2F5
Target/Specificity E2F-5 antibody detects endogenous levels of E2F-5.
Reconstitution & Storage Store at -20°C.
PrecautionsE2F5 Antibody (aa93-142) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name E2F5
Function Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Cellular Location Nucleus.
Volume 50 µl
Citations (0)
citation

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Background

Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor- initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.

References

Itoh A.,et al.Cell. Mol. Biol. Res. 41:147-154(1995).
Hijmans E.M.,et al.Mol. Cell. Biol. 15:3082-3089(1995).
Sardet C.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:2403-2407(1995).
Vaishnav Y.N.,et al.Biochem. Biophys. Res. Commun. 242:586-592(1998).
Li W.B.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# ALS16341
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