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RAPGEF5 / GFR Antibody (aa417-466)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q92565 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 68kDa |
| Dilution | ELISA (1:10000), IHC-P (20 µg/ml), WB (1:500-1:1000) |
| Gene ID | 9771 |
|---|---|
| Other Names | Rap guanine nucleotide exchange factor 5, Guanine nucleotide exchange factor for Rap1, M-Ras-regulated Rap GEF, MR-GEF, Related to Epac, Repac, RAPGEF5, GFR, KIAA0277, MRGEF |
| Target/Specificity | RAPGEF5 Antibodyantibody detects endogenous levels of RAPGEF5. |
| Reconstitution & Storage | Store at -20°C. |
| Precautions | RAPGEF5 / GFR Antibody (aa417-466) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RAPGEF5 |
|---|---|
| Synonyms | GFR, KIAA0277, MRGEF |
| Function | Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation. |
| Cellular Location | Nucleus. |
| Tissue Location | Widely expressed with highest levels in brain. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation.
References
Nagase T.,et al.DNA Res. 3:321-329(1996).
Scherer S.W.,et al.Science 300:767-772(2003).
Ichiba T.,et al.FEBS Lett. 457:85-89(1999).
de Rooij J.,et al.J. Biol. Chem. 275:20829-20836(2000).
Rebhun J.F.,et al.J. Biol. Chem. 275:34901-34908(2000).
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