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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   CD55 Antibody (aa71-330)   

CD55 Antibody (aa71-330)

Rabbit Polyclonal Antibody

     
  • ICC - CD55 Antibody (aa71-330) ALS16359
    Immunofluorescence of methanol-fixed HeLa using CD55 antibody at 1:200 dilution.
  • WB - CD55 Antibody (aa71-330) ALS16359
    Sample (30 ug of whole cell lysate). A: THP-1. 10% SDS PAGE. CD55 antibody diluted at 1:1000.
  • IHC - CD55 Antibody (aa71-330) ALS16359
    Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession P08174
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 41kDa
Dilution ICC (1:100-1:1000), IHC-P (5 µg/ml), WB (1:500-1:3000)
Additional Information
Gene ID 1604
Other Names Complement decay-accelerating factor, CD55, CD55, CR, DAF
Target/Specificity Human CD55
Reconstitution & Storage Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PrecautionsCD55 Antibody (aa71-330) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD55
Synonyms CR, DAF
Function This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted Isoform 5: Secreted Isoform 7: Cell membrane; Lipid-anchor, GPI-anchor
Tissue Location Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix
Volume 50 µl
Research Areas
Citations (0)

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Background

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

References

Caras I.W.,et al.Nature 325:545-549(1987).
Osuka F.,et al.Genomics 88:316-322(2006).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS16359
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