|Application ||WB, IHC-P|
|Dilution||IHC-P (5-10 µg/ml)|
|Other Names||Cholesterol side-chain cleavage enzyme, mitochondrial, 18.104.22.168, CYPXIA1, Cholesterol desmolase, Cytochrome P450 11A1, Cytochrome P450(scc), CYP11A1, CYP11A|
|Target/Specificity||Human P450SCC / CYP11A1|
|Reconstitution & Storage||Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||P450SCC / CYP11A1 Antibody (aa78-418) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.|
|Cellular Location||Mitochondrion membrane.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.
Chung B.-C.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8962-8966(1986).
Morohashi K.,et al.J. Biochem. 101:879-887(1987).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:671-675(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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