|Application ||WB, IHC-P|
|Dilution||IHC-P (5-10 µg/ml)|
|Other Names||Cholesterol side-chain cleavage enzyme, mitochondrial, 188.8.131.52, CYPXIA1, Cholesterol desmolase, Cytochrome P450 11A1, Cytochrome P450(scc), CYP11A1, CYP11A|
|Target/Specificity||Human P450SCC / CYP11A1|
|Reconstitution & Storage||Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||P450SCC / CYP11A1 Antibody (aa78-418) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.|
|Cellular Location||Mitochondrion membrane.|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.
Chung B.-C.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8962-8966(1986).
Morohashi K.,et al.J. Biochem. 101:879-887(1987).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:671-675(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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