|Application ||WB, IHC-P, ICC|
|Dilution||ICC (1:100-1:1000), IHC-P (5 µg/ml), WB (1:500-1:3000)|
|Other Names||15-hydroxyprostaglandin dehydrogenase [NAD(+)], 15-PGDH, 220.127.116.11, Prostaglandin dehydrogenase 1, HPGD, PGDH1|
|Target/Specificity||Human 15-PGDH / HPGD|
|Reconstitution & Storage||Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||15-PGDH / HPGD Antibody (aa205-266) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.|
|Tissue Location||Detected in colon epithelium (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
Krook M.,et al.Biochemistry 29:738-743(1990).
Ensor C.M.,et al.J. Biol. Chem. 265:14888-14891(1990).
Pichaud F.,et al.Gene 162:319-322(1995).
Delage-Mourroux R.,et al.Gene 188:143-148(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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