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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   15-PGDH / HPGD Antibody (aa205-266)   

15-PGDH / HPGD Antibody (aa205-266)

Rabbit Polyclonal Antibody

     
  • WB - 15-PGDH / HPGD Antibody (aa205-266) ALS16382
    Sample (30g whole cell lysate). A: Raji . 12% SDS PAGE. 15-PGDH / HPGD antibody diluted at 1:1000
  • ICC - 15-PGDH / HPGD Antibody (aa205-266) ALS16382
    Immunofluorescence of paraformaldehyde-fixed HeLa using 15-PGDH antibody at 1:200 dilution.
  • IHC - 15-PGDH / HPGD Antibody (aa205-266) ALS16382
    Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession P15428
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 29kDa
Dilution ICC (1:100-1:1000), IHC-P (5 µg/ml), WB (1:500-1:3000)
Additional Information
Gene ID 3248
Other Names 15-hydroxyprostaglandin dehydrogenase [NAD(+)], 15-PGDH, 1.1.1.141, Prostaglandin dehydrogenase 1, HPGD, PGDH1
Target/Specificity Human 15-PGDH / HPGD
Reconstitution & Storage Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Precautions15-PGDH / HPGD Antibody (aa205-266) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HPGD
Synonyms PGDH1, SDR36C1
Function Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
Cellular Location Cytoplasm.
Tissue Location Detected in colon epithelium (at protein level).
Research Areas
Citations (0)

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Background

Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.

References

Krook M.,et al.Biochemistry 29:738-743(1990).
Ensor C.M.,et al.J. Biol. Chem. 265:14888-14891(1990).
Pichaud F.,et al.Gene 162:319-322(1995).
Delage-Mourroux R.,et al.Gene 188:143-148(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS16382
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