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>   home   >   Products   >   Primary Antibodies   >   Cadherin Antibody (C-Terminus)   

Cadherin Antibody (C-Terminus)

Rabbit Polyclonal Antibody

  • IHC - Cadherin Antibody (C-Terminus) ALS16404
    Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC - Cadherin Antibody (C-Terminus) ALS16404
    Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P12830
Reactivity Human, Mouse, Rat, Chicken, Xenopus, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 97456 Da
Dilution IHC (1:100), IHC-P (1:100),
Additional Information
Gene ID 999
Other Names Cadherin-1, CAM 120/80, Epithelial cadherin, E-cadherin, Uvomorulin, CD324, E-Cad/CTF1, E-Cad/CTF2, E-Cad/CTF3, CDH1, CDHE, UVO
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsCadherin Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDH1
Synonyms CDHE, UVO
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Cellular Location Cell junction. Cell membrane; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Note=Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma- catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane
Tissue Location Non-neural epithelial tissues.
Volume 50 µl
Citations (0)

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$ 395.00
Cat# ALS16404
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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