Junctin / ASPH Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q12797 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 86kDa |
Dilution | IHC-P (5 µg/ml) |
Gene ID | 444 |
---|---|
Other Names | Aspartyl/asparaginyl beta-hydroxylase, 1.14.11.16, Aspartate beta-hydroxylase, ASP beta-hydroxylase, Peptide-aspartate beta-dioxygenase, ASPH, BAH |
Target/Specificity | Human Junctin / ASPH |
Reconstitution & Storage | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
Precautions | Junctin / ASPH Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ASPH |
---|---|
Synonyms | BAH |
Function | [Isoform 1]: Specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins. |
Cellular Location | [Isoform 1]: Endoplasmic reticulum membrane; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q28056} [Isoform 8]: Endoplasmic reticulum membrane; Single-pass type II membrane protein |
Tissue Location | Isoform 1 is detected in all tissues tested. Isoform 8 is mainly expressed in pancreas, heart, brain, kidney and liver. Isoform 8 is expressed in kidney (at protein level) |
Volume | 500 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Isoform 1: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins.
References
Korioth F.,et al.Gene 150:395-399(1994).
Lavaissiere L.,et al.J. Clin. Invest. 98:1313-1323(1996).
Lim K.Y.,et al.Gene 255:35-42(2000).
Dinchuk J.E.,et al.J. Biol. Chem. 275:39543-39554(2000).
Treves S.,et al.J. Biol. Chem. 275:39555-39568(2000).
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