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Cysteine Dioxygenase / CDO1 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q16878 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 23kDa |
| Dilution | IHC-P (10 µg/ml), WB (1-2 µg/ml), |
| Gene ID | 1036 |
|---|---|
| Other Names | Cysteine dioxygenase type 1, 1.13.11.20, Cysteine dioxygenase type I, CDO, CDO-I, CDO1 |
| Target/Specificity | CDO1 antibody is human, mouse and rat reactive. |
| Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Cysteine Dioxygenase / CDO1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CDO1 |
|---|---|
| Function | Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen. |
| Tissue Location | Highly expressed in liver and placenta. Low expression in heart, brain and pancreas. Also detected in hepatoblastoma Hep-G2 cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range.
References
McCann K.P.,et al.Biochim. Biophys. Acta 1209:107-110(1994).
Tsuboyama-Kasaoka N.,et al.Biosci. Biotechnol. Biochem. 63:1017-1024(1999).
Ramsden D.B.,et al.Mol. Pathol. 50:269-271(1997).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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