|Application ||WB, IHC-P, IF, E|
|Dilution||IF (20 µg/ml), IHC-P (10 µg/ml), WB (1-2 µg/ml)|
|Other Names||NADPH oxidase 3, 1.6.3.-, Mitogenic oxidase 2, MOX-2, gp91phox homolog 3, GP91-3, NOX3, MOX2|
|Target/Specificity||NOX3 antibody is human and mouse reactive. NOX3 is predicted to not cross-react with other NOX proteins.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||NOX3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.
Cheng G.,et al.Gene 269:131-140(2001).
Mungall A.J.,et al.Nature 425:805-811(2003).
Kikuchi H.,et al.Gene 254:237-243(2000).
Cheng G.,et al.J. Biol. Chem. 279:34250-34255(2004).
Ueno N.,et al.J. Biol. Chem. 280:23328-23339(2005).
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