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NOSTRIN Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - NOSTRIN Antibody (C-Terminus) ALS16431
    Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
    detail
  • IF - NOSTRIN Antibody (C-Terminus) ALS16431
    Immunofluorescence of NOSTRIN in mouse kidney tissue with NOSTRIN antibody at 20 ug/ml.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q8IVI9
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 58kDa
Dilution IF (20 µg/ml), IHC-P (10 µg/ml), WB (1-2 µg/ml)
Additional Information
Gene ID 115677
Other Names Nostrin, BM247 homolog, Nitric oxide synthase traffic inducer, Nitric oxide synthase trafficker, eNOS-trafficking inducer, NOSTRIN
Target/Specificity NOSTRIN antibody is human, mouse and rat reactive. At least four isoforms are known to exist; this antibody will detect all four isoforms.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsNOSTRIN Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NOSTRIN (HGNC:20203)
Function Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
Cellular Location [Isoform 1]: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Cytoplasm, cytoskeleton Note=Enriched in selected actin structures (PubMed:16234328, PubMed:16376344)
Tissue Location Expressed at highest levels in heart, kidney, placenta and lung, and at lowest levels in brain, thymus and spleen Present in vascular endothelial cells and placenta. Over-expressed in placenta from women with pre-eclampsia (at protein level)
Research Areas
Citations (0)
citation

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Background

Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.

References

Zimmermann K.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:17167-17172(2002).
Beese M.,et al.Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Li W.B.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# ALS16431
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