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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   NOSTRIN Antibody (C-Terminus)   

NOSTRIN Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - NOSTRIN Antibody (C-Terminus) ALS16431
    Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IF - NOSTRIN Antibody (C-Terminus) ALS16431
    Immunofluorescence of NOSTRIN in mouse kidney tissue with NOSTRIN antibody at 20 ug/ml.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q8IVI9
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 58kDa
Dilution IF (20 µg/ml), IHC-P (10 µg/ml), WB (1-2 µg/ml)
Additional Information
Gene ID 115677
Other Names Nostrin, BM247 homolog, Nitric oxide synthase traffic inducer, Nitric oxide synthase trafficker, eNOS-trafficking inducer, NOSTRIN
Target/Specificity NOSTRIN antibody is human, mouse and rat reactive. At least four isoforms are known to exist; this antibody will detect all four isoforms.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsNOSTRIN Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NOSTRIN
Function Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
Cellular Location Isoform 1: Cell membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasmic vesicle. Cytoplasm, cytoskeleton. Note=Enriched in selected actin structures (PubMed:16234328, PubMed:16376344)
Tissue Location Expressed at highest levels in heart, kidney, placenta and lung, and at lowest levels in brain, thymus and spleen. Present in vascular endothelial cells and placenta. Over- expressed in placenta from women with pre-eclampsia (at protein level).
Research Areas
Citations (0)

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Background

Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.

References

Zimmermann K.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:17167-17172(2002).
Beese M.,et al.Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Li W.B.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS16431
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