|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IF (20 µg/ml), IHC-P (10 µg/ml), WB (1-2 µg/ml)|
|Other Names||Nostrin, BM247 homolog, Nitric oxide synthase traffic inducer, Nitric oxide synthase trafficker, eNOS-trafficking inducer, NOSTRIN|
|Target/Specificity||NOSTRIN antibody is human, mouse and rat reactive. At least four isoforms are known to exist; this antibody will detect all four isoforms.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||NOSTRIN Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.|
|Cellular Location||Isoform 1: Cell membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasmic vesicle. Cytoplasm, cytoskeleton. Note=Enriched in selected actin structures (PubMed:16234328, PubMed:16376344)|
|Tissue Location||Expressed at highest levels in heart, kidney, placenta and lung, and at lowest levels in brain, thymus and spleen. Present in vascular endothelial cells and placenta. Over- expressed in placenta from women with pre-eclampsia (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
Zimmermann K.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:17167-17172(2002).
Beese M.,et al.Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Li W.B.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.