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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PDCL3 Antibody (C-Terminus)   

PDCL3 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - PDCL3 Antibody (C-Terminus) ALS16439
    Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC - PDCL3 Antibody (C-Terminus) ALS16439
    Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IF - PDCL3 Antibody (C-Terminus) ALS16439
    Immunofluorescence of PDCL3 in mouse liver tissue with PDCL3 antibody at 20 ug/mL.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q9H2J4
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 28kDa
Dilution IF (20 µg/ml), IHC-P (10 µg/ml), WB (1-2 µg/ml)
Additional Information
Gene ID 79031
Other Names Phosducin-like protein 3, HTPHLP, PhPL3, Viral IAP-associated factor 1, VIAF-1, PDCL3, PhLP2A, VIAF1
Target/Specificity PDCL3 antibody is human, mouse and rat reactive. PDCL3 antibody is predicted to not cross-react with other members of the PDCL protein family.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsPDCL3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDCL3
Synonyms PhLP2A, VIAF1
Function Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination.
Cellular Location Cytoplasm.
Tissue Location Expressed in all tissues examined including spleen, thymus, prostate, testis, ovary, small intestine and colon.
Research Areas
Citations (0)

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Background

Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination.

References

Wilkinson J.C.,et al.J. Biol. Chem. 279:51091-51099(2004).
Xu X.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS16439
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