|Application ||WB, IHC-P, E|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||PHD finger-like domain-containing protein 5A, PHD finger-like domain protein 5A, Splicing factor 3B-associated 14 kDa protein, SF3b14b, PHF5A|
|Target/Specificity||Human PHF5A / INI|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PHF5A / INI Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional regulator by binding to the GJA1/Cx43 promoter and enhancing its up-regulation by ESR1/ER- alpha. Also involved in pre-mRNA splicing.|
|Cellular Location||Nucleus. Nucleus speckle|
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Provided below are standard protocols that you may find useful for product applications.
Acts as a transcriptional regulator by binding to the GJA1/Cx43 promoter and enhancing its up-regulation by ESR1/ER- alpha. Also involved in pre-mRNA splicing.
Poleev A.,et al.Development 116:611-623(1992).
Kozmik Z.,et al.Mol. Cell. Biol. 13:6024-6035(1993).
Poleev A.,et al.Eur. J. Biochem. 228:899-911(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
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