AP1S3 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
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Primary Accession | Q96PC3 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 18kDa |
Dilution | IHC-P (10 µg/ml) |
Gene ID | 130340 |
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Other Names | AP-1 complex subunit sigma-3, Adaptor protein complex AP-1 subunit sigma-1C, Adaptor-related protein complex 1 subunit sigma-1C, Clathrin assembly protein complex 1 sigma-1C small chain, Golgi adaptor HA1/AP1 adaptin sigma-1C subunit, Sigma 1C subunit of AP-1 clathrin, Sigma-adaptin 1C, Sigma1C-adaptin, AP1S3 |
Target/Specificity | Human AP1S3 |
Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | AP1S3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AP1S3 |
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Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking (PubMed:24791904). |
Cellular Location | Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin- coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex |
Tissue Location | Widely expressed. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
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