DAOA Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P59103 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 18kDa |
Dilution | IHC-P (10 µg/ml) |
Gene ID | 267012 |
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Other Names | D-amino acid oxidase activator, Protein G72, DAOA, G72 |
Target/Specificity | Human DAOA |
Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | DAOA Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DAOA |
---|---|
Synonyms | G72 |
Function | May suppress DAO (D-amino acid oxidase) and SOD1 activity and promote their degradation (PubMed:18544534, PubMed:20521334, PubMed:21679769, PubMed:30037290). Has conversely also been suggested to function as a DAO activator (PubMed:12364586, PubMed:24362575, PubMed:29114206). May stimulate the degradation of DDO (D-aspartate oxidase) (PubMed:37805834). May play a role in mitochondrial fission (PubMed:17684499). |
Cellular Location | Cytoplasm, cytosol. Golgi apparatus. Mitochondrion. Note=May transiently pass through the Golgi apparatus |
Tissue Location | Expressed in the amygdala and in astrocytes of the cortex (at protein level) (PubMed:18544534, PubMed:17684499, PubMed:12364586). Expressed in the caudate nucleus, spinal cord and testis (PubMed:12364586). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Seems to activate D-amino acid oxidase.
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