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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   PLAT / TPA Antibody   

PLAT / TPA Antibody

Rabbit Polyclonal Antibody

     
  • WB - PLAT / TPA Antibody ALS16494
    Western blot analysis of extracts of various cell lines, using PLAT antibody.
  • IHC - PLAT / TPA Antibody ALS16494
    Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P00750
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 63kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:2000),
Additional Information
Gene ID 5327
Other Names Tissue-type plasminogen activator, t-PA, t-plasminogen activator, tPA, 3.4.21.68, Alteplase, Reteplase, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, PLAT
Target/Specificity Human PLAT / TPA
Reconstitution & Storage Long term: -80°C; Short term: -20°C. Avoid freeze-thaw cycles.
PrecautionsPLAT / TPA Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLAT
Function Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration.
Cellular Location Secreted, extracellular space.
Tissue Location Synthesized in numerous tissues (including tumors) and secreted into most extracellular body fluids, such as plasma, uterine fluid, saliva, gingival crevicular fluid, tears, seminal fluid, and milk
Volume 50 µl
Research Areas
Citations (0)

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Background

Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration.

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$ 395.00
Cat# ALS16494
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Availability: 5 days
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