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LIPG / Endothelial Lipase Antibody (aa19-32)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q9Y5X9 |
| Other Accession | 9388 |
| Reactivity | Human, Mouse, Rat, Pig, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 56795 Da |
| Dilution | IHC-P (5 µg/ml), |
| Gene ID | 9388 |
|---|---|
| Other Names | LIPG, EDL, EL, Lipoprotein lipase H, Lipase, endothelial, PRO719, Endothelial lipase |
| Target/Specificity | human endothelial lipase amino acids 19-32 |
| Reconstitution & Storage | TBS, pH 7.4, 0.02% sodium azide, 0.5 mg/ml BSA, 50% glycerol. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | LIPG / Endothelial Lipase Antibody (aa19-32) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LIPG |
|---|---|
| Function | Exerts both phospholipase and triglyceride lipase activities (PubMed:12032167, PubMed:10318835, PubMed:10192396). More active as a phospholipase than a triglyceride lipase (PubMed:12032167). Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates (PubMed:12032167). Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins (PubMed:12032167, PubMed:10192396). |
| Cellular Location | Secreted. |
| Tissue Location | High level of expression in the liver, placenta, lung, thyroid, kidney, testis and in the corpus luteum of the ovary Expressed also in coronary artery endothelial cells, umbilical vein endothelial cells and in hepatocytes and osteosarcoma cell lines. Not detected in heart, brain and muscle. |
| Volume | 100 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin.
References
Hirata K.,et al.J. Biol. Chem. 274:14170-14175(1999).
Jaye M.,et al.Nat. Genet. 21:424-428(1999).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
McCoy M.G.,et al.J. Lipid Res. 43:921-929(2002).
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