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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KLKB1 / Plasma Kallikrein Antibody (aa341-390)   

KLKB1 / Plasma Kallikrein Antibody (aa341-390)

Rabbit Polyclonal Antibody

     
  • IHC - KLKB1 / Plasma Kallikrein Antibody (aa341-390) ALS16554
    Anti-KLKB1 / Plasma Kallikrein antibody IHC staining of human breast.
  • WB - KLKB1 / Plasma Kallikrein Antibody (aa341-390) ALS16554
    Western blot of extracts from HeLa cells, using KLKB1 (heavy chain, Cleaved-Arg390) Antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P03952
Other Accession 3818
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 71370 Da
Dilution ELISA (1:10000), IHC-P (20 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 3818
Other Names KLKB1, Fletcher factor deficiency, Fletcher factor, Kininogenin, Plasma kallikrein, PKK deficiency, Plasma kallikrein heavy chain, PPK, Prekallikrein deficiency, Plasma kallikrein light chain, Plasma prekallikrein, Kallikrein 3
Target/Specificity KLKB1 (heavy chain,Cleaved-Arg390) Antibody detects endogenous levels of fragment of activated KLKB1 resulting from cleavage adjacent to Arg390.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsKLKB1 / Plasma Kallikrein Antibody (aa341-390) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLKB1
Synonyms KLK3
Function The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Cellular Location Secreted.
Volume 50 µl
Research Areas
Citations (0)

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Background

The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.

References

Chung D.W.,et al.Biochemistry 25:2410-2417(1986).
Yu H.,et al.Genomics 69:225-234(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS16554
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