|Application ||WB, IHC-P|
|Calculated MW||50077 Da|
|Dilution||IHC-P (1:100), WB (1:1000 - 1:4000),|
|Other Names||PLA2G7, GVIIA-PLA2, PAF acetylhydrolase, PAFAD, PAF 2-acylhydrolase, PAFAH, LDL-PLA(2), LP-PLA2, Group-VIIA phospholipase A2, LDL-PLA2|
|Target/Specificity||This Polyclonal antibody is directed against human PAF Acetylhydrolase protein. The product was purified from serum by protein A chromatography. Expect reactivity with human PAF Acetylhydrolase. Cross-reactivity with PAF Acetylhydrolase from other so ...|
|Reconstitution & Storage||PBS, pH 7.4, 0.02% sodium azide. Store at -20°C for up to one year.|
|Precautions||LP-PLA2 / PLA2G7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.|
|Cellular Location||Secreted, extracellular space.|
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Provided below are standard protocols that you may find useful for product applications.
Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.
Tjoelker L.W.,et al.Nature 374:549-553(1995).
Tew D.G.,et al.Arterioscler. Thromb. Vasc. Biol. 16:591-599(1996).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Tjoelker L.W.,et al.J. Biol. Chem. 270:25481-25487(1995).
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