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JCHAIN / Ig J Chain Antibody (clone 3H7)

Mouse Monoclonal Antibody

     
  • IHC - JCHAIN / Ig J Chain Antibody (clone 3H7) ALS16557
    Anti-IGJ antibody IHC staining of human breast.
  • WB - JCHAIN / Ig J Chain Antibody (clone 3H7) ALS16557
    HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IGJ...
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P01591
Other Accession 3512
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 3H7
Calculated MW 18099 Da
Dilution IHC-P (10 µg/ml), WB (1:2000),
Additional Information
Gene ID 3512
Other Names JCHAIN, IGCJ, Immunoglobulin J chain, IGJ, IgJ chain, JCH
Target/Specificity Human IGJ
Reconstitution & Storage PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.
PrecautionsJCHAIN / Ig J Chain Antibody (clone 3H7) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IGJ
Synonyms IGCJ
Function Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
Cellular Location Secreted.
Volume 50 µl
Research Areas
Citations (0)

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Background

Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mole J.E.,et al.Biochemistry 16:3507-3513(1977).
Max E.E.,et al.J. Exp. Med. 161:832-849(1985).
Frutiger S.,et al.Biochemistry 31:12643-12647(1992).
Kristiansen T.Z.,et al.Mol. Cell. Proteomics 3:715-728(2004).

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$ 395.00
Cat# ALS16557
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