CYPOR / POR Antibody (clone 6C4)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, FC |
---|---|
Primary Accession | P16435 |
Other Accession | 5447 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Clone Names | 6C4 |
Calculated MW | 76690 Da |
Dilution | Flo (1:100), IF (1:50 - 1:100), IHC-P (1:50 - 1:100), WB (1:2000), |
Gene ID | 5447 |
---|---|
Other Names | POR, CPR, CYPOR, p450R |
Target/Specificity | Human CYPOR / POR |
Reconstitution & Storage | PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing. |
Precautions | CYPOR / POR Antibody (clone 6C4) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | POR {ECO:0000255|HAMAP-Rule:MF_03212} |
---|---|
Synonyms | CYPOR |
Function | This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. |
Cellular Location | Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03212}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03212}; Cytoplasmic side {ECO:0000255|HAMAP- Rule:MF_03212} |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.
References
Shephard E.A.,et al.Arch. Biochem. Biophys. 294:168-172(1992).
Czerwinski M.,et al.Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
Murakami H.O.,et al.Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 424:157-164(2003).
Haniu M.,et al.Biochemistry 28:8639-8645(1989).
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