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FCGR1A / CD64 Antibody (clone 3D3)

Mouse Monoclonal Antibody

     
  • IHC - FCGR1A / CD64 Antibody (clone 3D3) ALS16575
    Anti-FCGR1A / CD64 antibody IHC staining of human tonsil.
    detail
  • IF - FCGR1A / CD64 Antibody (clone 3D3) ALS16575
    Anti-FCGR1A mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently...
    detail
  • WB - FCGR1A / CD64 Antibody (clone 3D3) ALS16575
    HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FCGR1A...
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession P12314
Other Accession 2209
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 3D3
Calculated MW 42632 Da
Dilution IF (1:100), IHC-P (10 µg/ml), WB (1:4000),
Additional Information
Gene ID 2209
Other Names FCGR1A, CD64A, CD64, CD64 antigen, FCG1, FcgammaRIa, IGFR1, IgG Fc receptor I, Fc-gamma receptor I A1, Fc-gamma RIA, FCGR1, Fc gamma receptor, Fc-gamma RI, FCRI
Target/Specificity Human CD64
Reconstitution & Storage PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.
PrecautionsFCGR1A / CD64 Antibody (clone 3D3) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FCGR1A
Synonyms FCG1, FCGR1, IGFR1
Function High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells.
Cellular Location Cell membrane; Single-pass type I membrane protein Note=Stabilized at the cell membrane through interaction with FCER1G
Tissue Location Monocyte/macrophage specific.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.

References

Allen J.M.,et al.Nucleic Acids Res. 16:11824-11824(1988).
Allen J.M.,et al.Science 243:378-381(1989).
Porges A.J.,et al.J. Clin. Invest. 90:2102-2109(1992).
Benech P.D.,et al.J. Exp. Med. 176:1115-1123(1992).
Gregory S.G.,et al.Nature 441:315-321(2006).

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$ 467.50
Cat# ALS16575
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