|Application ||WB, IHC-P|
|Calculated MW||52391 Da|
|Dilution||IHC-P (1:150), WB (1:2000),|
|Other Names||SELENBP1, HSBP, HSP56, SBP56, Selenium-binding protein 1, SBP, SP56, LPSB, Selenium binding protein 1|
|Target/Specificity||Human SELENBP1 / SP56|
|Reconstitution & Storage||PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.|
|Precautions||Selenium Binding Protein 1 Antibody (clone 3D4) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity).|
|Cellular Location||Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=May associate with Golgi membrane. May associate with the membrane of autophagosomes (By similarity).|
|Tissue Location||Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients|
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Provided below are standard protocols that you may find useful for product applications.
Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity).
Chang P.W.G.,et al.J. Cell. Biochem. 64:217-224(1997).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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