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CRYM Antibody (clone 1G7)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, Flo |
|---|---|
| Primary Accession | Q14894 |
| Other Accession | 1428 |
| Reactivity | Human, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Clone Names | 1G7 |
| Calculated MW | 33776 Da |
| Dilution | Flo (1:100), IF (1:100), IHC-P (1:150), WB (1:500 - 1:2000), |
| Gene ID | 1428 |
|---|---|
| Other Names | CRYM, Crystallin, mu, Ketimine reductase, Mu-crystallin homolog, THBP, DFNA40 |
| Target/Specificity | Human CRYM |
| Reconstitution & Storage | PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing. |
| Precautions | CRYM Antibody (clone 1G7) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CRYM |
|---|---|
| Synonyms | THBP |
| Function | Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Expressed in neural tissue, muscle and kidney. |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors.
References
Segovia L.,et al.Mol. Vis. 3:9-9(1997).
Vie M.-P.,et al.Mol. Endocrinol. 11:1728-1736(1997).
Sperbeck S.J.,et al.Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.
Loftus B.J.,et al.Genomics 60:295-308(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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