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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CRYM Antibody (clone 1G7)   

CRYM Antibody (clone 1G7)

Mouse Monoclonal Antibody

     
  • IHC - CRYM Antibody (clone 1G7) ALS16586
    Anti-CRYM antibody IHC staining of human kidney.
  • IF - CRYM Antibody (clone 1G7) ALS16586
    Anti-CRYM mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently...
  • WB - CRYM Antibody (clone 1G7) ALS16586
    HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CRYM...
  • WB - CRYM Antibody (clone 1G7) ALS16586
    Western blot of extracts (35 ug) from 9 different cell lines by using anti-CRYM monoclonal antibody.
  • FC - CRYM Antibody (clone 1G7) ALS16586
    HEK293T cells transfected with either overexpress plasmid (Red) or empty vector control plasmid...
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, Flo
Primary Accession Q14894
Other Accession 1428
Reactivity Human, Rat
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names 1G7
Calculated MW 33776 Da
Dilution Flo (1:100), IF (1:100), IHC-P (1:150), WB (1:500 - 1:2000),
Additional Information
Gene ID 1428
Other Names CRYM, Crystallin, mu, Ketimine reductase, Mu-crystallin homolog, THBP, DFNA40
Target/Specificity Human CRYM
Reconstitution & Storage PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.
PrecautionsCRYM Antibody (clone 1G7) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRYM
Synonyms THBP
Function Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors.
Cellular Location Cytoplasm.
Tissue Location Expressed in neural tissue, muscle and kidney.
Volume 50 µl
Research Areas
Citations (0)

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Background

Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors.

References

Segovia L.,et al.Mol. Vis. 3:9-9(1997).
Vie M.-P.,et al.Mol. Endocrinol. 11:1728-1736(1997).
Sperbeck S.J.,et al.Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.
Loftus B.J.,et al.Genomics 60:295-308(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS16586
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