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SPAG16 Antibody (Internal)

Goat Polyclonal Antibody

     
  • IHC - SPAG16 Antibody (Internal) ALS16599
    Human, TestisL Formalin-Fixed Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q8N0X2
Other Accession 79582
Reactivity Human, Mouse, Rat, Pig, Horse
Host Goat
Clonality Polyclonal
Calculated MW 70818 Da
Dilution ELISA (1:32000), IHC-P (5 µg/ml),
Additional Information
Gene ID 79582
Other Names SPAG16, Pf20 protein homolog, WDR29, PF20, Sperm associated antigen 16, WD repeat domain 29
Target/Specificity Human SPAG16. This antibody is expected to recognize isoform 1 (NP_078808.3) only.
Reconstitution & Storage Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.
PrecautionsSPAG16 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPAG16
Synonyms PF20
Function Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia (By similarity).
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, cilium axoneme. Note=Detected on the sperm flagellum axoneme. Detected in the central apparatus of the axoneme. Colocalizes with SPAG6 on microtubules (By similarity)
Tissue Location Isoform 1 is detected in testis. Isoform 4 is detected in testis and brain, and at lower levels in kidney, heart, pancreas, thyroid, ovary, adrenal gland, spinal cord, trachea and liver.
Research Areas
Citations (0)

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Background

Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia (By similarity).

References

Pennarun G.,et al.Am. J. Respir. Cell Mol. Biol. 26:362-370(2002).
Zhang Z.,et al.Mol. Cell. Biol. 22:7993-8004(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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$ 395.00
Cat# ALS16599
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