|Application ||WB, IHC-P, E|
|Calculated MW||62750 Da|
|Dilution||ELISA (1:20000 - 1:80000), IHC-P (5 µg/ml), WB (1:1000 - 1:2000),|
|Other Names||AMHR2, AMH type II receptor, AMHR, MIS type II receptor, MISR2, MISRII, MRII|
|Target/Specificity||Human AMHR2 / MISRII.|
|Reconstitution & Storage||PBS, pH 7.4, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||AMHR2 / MISRII Antibody (aa207-440) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Imbeaud S.,et al.Nat. Genet. 11:382-388(1995).
Visser J.A.,et al.Biochem. Biophys. Res. Commun. 215:1029-1036(1995).
Masiakos P.T.,et al.Clin. Cancer Res. 5:3488-3499(1999).
Li H.,et al.Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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