KRT8 / CK8 / Cytokeratin 8 Antibody (clone AT3D11)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P05787 |
Other Accession | 3856 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG3,k |
Clone Names | AT3D11 |
Calculated MW | 53704 Da |
Dilution | IHC-P (10 µg/ml), WB (1:1000), |
Gene ID | 3856 |
---|---|
Other Names | KRT8, CARD2, CK-8, CYK8, Cytokeratin-8, CK8, K2C8, K8, KO, Keratin-8, Type-II keratin Kb8, Cytokeratin 8, Keratin 8 |
Target/Specificity | Human KRT8 / CK8 / Cytokeratin 8 |
Reconstitution & Storage | Supplied in PBS, pH 7.4, 10% glycerol, 0.02% sodium azide. Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles. |
Precautions | KRT8 / CK8 / Cytokeratin 8 Antibody (clone AT3D11) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KRT8 |
---|---|
Synonyms | CYK8 |
Function | Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
Cellular Location | Cytoplasm. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q10758}. Nucleus matrix {ECO:0000250|UniProtKB:Q10758} |
Tissue Location | Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
References
Krauss S.,et al.Gene 86:241-249(1990).
Yamamoto R.,et al.Mol. Endocrinol. 4:370-374(1990).
Waseem A.,et al.New Biol. 2:464-478(1990).
Ku N.-O.,et al.J. Biol. Chem. 272:7556-7564(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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