|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||61987 Da|
|Dilution||ELISA (1:20000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),|
|Other Names||CYP2U1, p450TEC, SPG49, Cytochrome P450 2U1|
|Target/Specificity||Cytochrome P450 2U1 Antibody detects endogenous levels of total Cytochrome P450 2U1 protein.|
|Reconstitution & Storage||PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.|
|Precautions||CYP2U1 Antibody (aa281-330) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane|
|Tissue Location||Widely expressed with stronger expression in thymus, heart and cerebellum.|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes.
Chuang S.S.,et al.J. Biol. Chem. 279:6305-6314(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Karlgren M.,et al.Biochem. Biophys. Res. Commun. 315:679-685(2004).
Choudhary D.,et al.Arch. Biochem. Biophys. 436:50-61(2005).
Tesson C.,et al.Am. J. Hum. Genet. 91:1051-1064(2012).
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