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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AGPAT3 Antibody (aa121-170)   

AGPAT3 Antibody (aa121-170)

Rabbit Polyclonal Antibody

     
  • IHC - AGPAT3 Antibody (aa121-170) ALS16635
    Anti-AGPAT3 antibody IHC staining of human kidney.
  • WB - AGPAT3 Antibody (aa121-170) ALS16635
    Western blot of extracts from K562 cells, using AGPAT3 Antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9NRZ7
Other Accession 56894
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 43381 Da
Dilution ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 56894
Other Names AGPAT3, 1-AGP acyltransferase 3, 1-AGPAT 3, LPAAT3, LPAAT-gamma, LPAAT-GAMMA1
Target/Specificity AGPAT3 Antibody detects endogenous levels of total AGPAT3 protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsAGPAT3 Antibody (aa121-170) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGPAT3
Synonyms LPAAT3
Function Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA (PubMed:21173190). Has a preference for arachidonoyl-CoA as a donor. Has also a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol (By similarity).
Cellular Location Endoplasmic reticulum membrane; Multi- pass membrane protein. Nucleus envelope
Tissue Location Widely expressed with highest levels in testis, pancreas and kidney, followed by spleen, lung, adipose tissue and liver.
Volume 50 µl
Research Areas
Citations (0)

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Background

Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA.

References

Leung D.W.,et al.Front. Biosci. 6:D944-D953(2001).
Nagamine K.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Hattori M.,et al.Nature 405:311-319(2000).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS16635
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