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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CDC42EP2 Antibody (aa10-59)   

CDC42EP2 Antibody (aa10-59)

Rabbit Polyclonal Antibody

     
  • IHC - CDC42EP2 Antibody (aa10-59) ALS16645
    Anti-CDC42EP2 antibody IHC staining of human kidney.
  • WB - CDC42EP2 Antibody (aa10-59) ALS16645
    Western blot of extracts from K562 cells, using BORG1 Antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O14613
Other Accession 10435
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 22484 Da
Dilution ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 10435
Other Names CDC42EP2, Binder of Rho GTPases 1, BORG1, Cdc42 effector protein 2, CRIB-containing BOGR1 protein, CEP2
Target/Specificity BORG1 Antibody detects endogenous levels of total BORG1 protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsCDC42EP2 Antibody (aa10-59) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDC42EP2
Synonyms BORG1, CEP2
Function Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
Cellular Location Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton
Tissue Location Highly expressed in the heart. Weakly expressed in the pancreas and liver
Volume 50 µl
Research Areas
Citations (0)

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Background

Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.

References

Guru S.C.,et al.Genome Res. 7:725-735(1997).
Joberty G.,et al.Mol. Cell. Biol. 19:6585-6597(1999).
Hirsch D.S.,et al.J. Biol. Chem. 276:875-883(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS16645
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