|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||22484 Da|
|Dilution||ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),|
|Other Names||CDC42EP2, Binder of Rho GTPases 1, BORG1, Cdc42 effector protein 2, CRIB-containing BOGR1 protein, CEP2|
|Target/Specificity||BORG1 Antibody detects endogenous levels of total BORG1 protein.|
|Reconstitution & Storage||PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.|
|Precautions||CDC42EP2 Antibody (aa10-59) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.|
|Cellular Location||Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton|
|Tissue Location||Highly expressed in the heart. Weakly expressed in the pancreas and liver|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
Guru S.C.,et al.Genome Res. 7:725-735(1997).
Joberty G.,et al.Mol. Cell. Biol. 19:6585-6597(1999).
Hirsch D.S.,et al.J. Biol. Chem. 276:875-883(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.