|Application ||WB, IHC-P|
|Calculated MW||28837 Da|
|Dilution||IHC-P (1:100), WB (1:50),|
|Other Names||CTSG, CATG, Cathepsin G, CG|
|Target/Specificity||Recognizes human Cathepsin G.|
|Reconstitution & Storage||Tissue culture supernatant, 15 mM sodium azide. May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C.|
|Precautions||CTSG / Cathepsin G Antibody (N-Terminus, clone 9i239) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride.|
|Cellular Location||Cell surface.|
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Provided below are standard protocols that you may find useful for product applications.
Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride.
Salvesen G.,et al.Biochemistry 26:2289-2293(1987).
Hohn P.A.,et al.J. Biol. Chem. 264:13412-13419(1989).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Avril L.E.,et al.FEBS Lett. 345:81-86(1994).
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