|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||24422 Da|
|Dilution||ELISA (1:20000), IF (1:100 - 1:500), IHC-P (10 µg/ml), WB (1:500 - 1:1000),|
|Other Names||KDELR2, ERD2-like protein 1, ERD2.2, ERD-2-like protein, KDEL receptor 2, ELP-1|
|Target/Specificity||ERD22 Antibody detects endogenous levels of total ERD22 protein.|
|Reconstitution & Storage||PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.|
|Precautions||KDELR2 Antibody (aa81-130) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L.
Lewis M.J.,et al.J. Mol. Biol. 226:913-916(1992).
Hsu V.W.,et al.Cell 69:625-635(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Scherer S.W.,et al.Science 300:767-772(2003).
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