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NDUFV2 Antibody (aa20-69)

Rabbit Polyclonal Antibody

     
  • IHC - NDUFV2 Antibody (aa20-69) ALS16673
    Anti-NDUFV2 antibody IHC staining of human kidney.
    detail
  • IHC - NDUFV2 Antibody (aa20-69) ALS16673
    Anti-NDUFV2 antibody IHC staining of human liver.
    detail
  • WB - NDUFV2 Antibody (aa20-69) ALS16673
    Western blot of extracts from Jurkat/HeLa/HepG2/MCF-7 cells, using NDUFV2 Antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P19404
Other Accession 4729
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 27392 Da
Dilution ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 4729
Other Names NDUFV2, Complex I 24kDa subunit, CI-24k
Target/Specificity NDUFV2 Antibody detects endogenous levels of total NDUFV2 protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsNDUFV2 Antibody (aa20-69) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NDUFV2 (HGNC:7717)
Function Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (Probable). Parts of the peripheral arm of the enzyme, where the electrons from NADH are accepted by flavin mononucleotide (FMN) and then passed along a chain of iron-sulfur clusters by electron tunnelling to the final acceptor ubiquinone (Probable). Contains one iron-sulfur cluster (Probable).
Cellular Location Mitochondrion inner membrane {ECO:0000250|UniProtKB:P04394}; Peripheral membrane protein {ECO:0000250|UniProtKB:P04394}; Matrix side {ECO:0000250|UniProtKB:P04394}
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

References

Pilkington S.J.,et al.Biochemistry 28:3257-3264(1989).
Murray J.,et al.J. Biol. Chem. 278:13619-13622(2003).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Ogura M.,et al.Biochem. J. 447:281-289(2012).

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Discontinued
Cat# ALS16673
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