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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RAB11FIP4 / RAB11-FIP4 Antibody (aa452-501)   

RAB11FIP4 / RAB11-FIP4 Antibody (aa452-501)

Rabbit Polyclonal Antibody

     
  • IHC - RAB11FIP4 / RAB11-FIP4 Antibody (aa452-501) ALS16678
    Anti-RAB11FIP4 / RAB11-FIP4 antibody IHC staining of human tonsil.
  • WB - RAB11FIP4 / RAB11-FIP4 Antibody (aa452-501) ALS16678
    Western blot of extracts from 293/COLO/HUVEC/HepG2/HT-29 cells, using RAB11FIP4 Antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession Q86YS3
Other Accession 84440
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 71928 Da
Dilution ELISA (1:40000), IHC (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 84440
Other Names RAB11FIP4, FIP4-Rab11, KIAA1821, ARFO2, Arfophilin-2, RAB11-FIP4
Target/Specificity RAB11FIP4 Antibody detects endogenous levels of total RAB11FIP4 protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsRAB11FIP4 / RAB11-FIP4 Antibody (aa452-501) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB11FIP4
Synonyms ARFO2, KIAA1821
Function Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6.
Cellular Location Endosome. Cytoplasm, cytoskeleton, spindle Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Recycling endosome membrane; Peripheral membrane protein Cleavage furrow. Midbody Cytoplasmic vesicle. Note=Recruited to the cleavage furrow and the midbody during cytokinesis
Tissue Location Present at high level in testis (at protein level). Weakly expressed in other tissues
Volume 50 µl
Research Areas
Citations (0)

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Background

Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6.

References

Wallace D.M.,et al.Biochem. Biophys. Res. Commun. 299:770-779(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Jenne D.E.,et al.Genes Chromosomes Cancer 37:111-120(2003).
Nagase T.,et al.DNA Res. 8:85-95(2001).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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$ 395.00
Cat# ALS16678
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