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RAP2C Antibody (aa97-146)

Rabbit Polyclonal Antibody

     
  • IHC - RAP2C Antibody (aa97-146) ALS16683
    Anti-RAP2C antibody IHC staining of human colon.
    detail
  • WB - RAP2C Antibody (aa97-146) ALS16683
    Western blot of extracts from Jurkat/MCF-7 cells, using RAP2C Antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9Y3L5
Other Accession 57826
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 20745 Da
Dilution ELISA (1:10000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 57826
Other Names RAP2C, Ras-related protein Rap-2c, Small GTPase RAP2C
Target/Specificity RAP2C Antibody detects endogenous levels of total RAP2C protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsRAP2C Antibody (aa97-146) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAP2C
Function Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription.
Cellular Location Cytoplasm. Recycling endosome membrane; Lipid-anchor; Cytoplasmic side
Tissue Location Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription.

References

Guo Z.,et al.Mol. Biol. Rep. 34:137-144(2007).
Rhodes S.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# ALS16683
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