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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   SEPT7 / Septin 7 Antibody (aa350-399)   

SEPT7 / Septin 7 Antibody (aa350-399)

Rabbit Polyclonal Antibody

     
  • IHC - SEPT7 / Septin 7 Antibody (aa350-399) ALS16684
    Anti-SEPT7 / Septin 7 antibody IHC staining of human brain, cerebellum.
  • IHC - SEPT7 / Septin 7 Antibody (aa350-399) ALS16684
    Anti-SEPT7 / Septin 7 antibody IHC staining of human kidney.
  • WB - SEPT7 / Septin 7 Antibody (aa350-399) ALS16684
    Western blot of extracts from HeLa/HUVEC/MCF-7 cells, using SEPT7 Antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q16181
Other Accession 989
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 50680 Da
Dilution ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 989
Other Names SEPT7, CDC10, CDC10 protein homolog, Hcdc10, NBLA02942, Sep7, SEPT7A, Septin 7, Septin-7, CDC3
Target/Specificity SEPT7 Antibody detects endogenous levels of total SEPT7 protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsSEPT7 / Septin 7 Antibody (aa350-399) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEPT7
Synonyms CDC10
Function Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements.
Cellular Location Cytoplasm. Chromosome, centromere, kinetochore Cytoplasm, cytoskeleton, spindle Cleavage furrow. Midbody. Cytoplasm, cytoskeleton, cilium axoneme. Note=Distributed throughout the cytoplasm in prometaphase cells. Associated with the spindle during metaphase. Associated with the central spindle and at the cleavage furrow in anaphase cells. Detected at the midbody in telophase Associated with actin stress fibers (By similarity)
Tissue Location Widely expressed.
Volume 50 µl
Research Areas
Citations (0)

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Background

Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements.

References

Nakatsuru S.,et al.Biochem. Biophys. Res. Commun. 202:82-87(1994).
Nagata K.,et al.J. Biol. Chem. 279:55895-55904(2004).
Hall P.A.,et al.J. Pathol. 206:269-278(2005).
Kremer B.E.,et al.Mol. Biol. Cell 16:4648-4659(2005).
Rush J.,et al.Nat. Biotechnol. 23:94-101(2005).

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$ 395.00
Cat# ALS16684
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