|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||82144 Da|
|Dilution||ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),|
|Other Names||Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, 220.127.116.11, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, EEF2K|
|Target/Specificity||eEF2K Antibody detects endogenous levels of total eEF2K protein.|
|Reconstitution & Storage||PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.|
|Precautions||EEF2K Antibody (aa336-385) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.|
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