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TACC1 Antibody (aa11-60)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | O75410 |
| Other Accession | 6867 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 87794 Da |
| Dilution | ELISA (1:10000), IF (1:100 - 1:500), IHC-P (10 µg/ml), WB (1:500 - 1:1000), |
| Gene ID | 6867 |
|---|---|
| Other Names | TACC1, Ga55, Gastric cancer antigen Ga55, KIAA1103, Taxin-1 |
| Target/Specificity | TACC1 Antibody detects endogenous levels of total TACC1 protein. |
| Reconstitution & Storage | PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year. |
| Precautions | TACC1 Antibody (aa11-60) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TACC1 |
|---|---|
| Synonyms | KIAA1103 |
| Function | Involved in transcription regulation induced by nuclear receptors, including in T3 thyroid hormone and all-trans retinoic acid pathways (PubMed:20078863). Might promote the nuclear localization of the receptors (PubMed:20078863). Likely involved in the processes that promote cell division prior to the formation of differentiated tissues. |
| Cellular Location | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Nucleus during interphase. Weakly concentrated at centrosomes during mitosis and colocalizes with AURKC at the midbody during cytokinesis. [Isoform 10]: Cytoplasm |
| Tissue Location | Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.
References
Still I.H.,et al.Oncogene 18:4032-4038(1999).
Still I.H.,et al.BMC Evol. Biol. 4:16-16(2004).
Li F.,et al.Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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