|Application ||WB, IHC-P, IF, E|
|Calculated MW||87794 Da|
|Dilution||ELISA (1:10000), IF (1:100 - 1:500), IHC-P (10 µg/ml), WB (1:500 - 1:1000),|
|Other Names||TACC1, Ga55, Gastric cancer antigen Ga55, KIAA1103, Taxin-1|
|Target/Specificity||TACC1 Antibody detects endogenous levels of total TACC1 protein.|
|Reconstitution & Storage||PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.|
|Precautions||TACC1 Antibody (aa11-60) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.|
|Cellular Location||Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Nucleus during interphase. Weakly concentrated at centrosomes during mitosis and colocalizes with AURKC at the midbody during cytokinesis|
|Tissue Location||Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer.|
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Provided below are standard protocols that you may find useful for product applications.
Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.
Still I.H.,et al.Oncogene 18:4032-4038(1999).
Still I.H.,et al.BMC Evol. Biol. 4:16-16(2004).
Li F.,et al.Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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