|Application ||WB, IHC-P, E|
|Calculated MW||12074 Da|
|Dilution||ELISA (1:1000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),|
|Other Names||TUSC2, C3orf11, Fus-1 protein, FUS1, Fusion 1 protein, LGCC, PAP, PDAP2, PDGFA-associated protein 2, PDGFA associated protein 2, Tumor suppressor candidate 2|
|Target/Specificity||TUSC2 Antibody detects endogenous levels of total TUSC2 protein.|
|Reconstitution & Storage||PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.|
|Precautions||TUSC2 / PAP Antibody (aa41-90) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C3orf11, FUS1, LGCC, PDAP2|
|Function||May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.|
|Tissue Location||Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta|
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Provided below are standard protocols that you may find useful for product applications.
May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.
Kondo M.,et al.Oncogene 20:6258-6262(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Uno F.,et al.Cancer Res. 64:2969-2976(2004).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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