Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
TUSC2 / PAP Antibody (aa41-90)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | O75896 |
| Other Accession | 11334 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 12074 Da |
| Dilution | ELISA (1:1000), IHC-P (10 µg/ml), WB (1:500 - 1:1000), |
| Gene ID | 11334 |
|---|---|
| Other Names | TUSC2, C3orf11, Fus-1 protein, FUS1, Fusion 1 protein, LGCC, PAP, PDAP2, PDGFA-associated protein 2, PDGFA associated protein 2, Tumor suppressor candidate 2 |
| Target/Specificity | TUSC2 Antibody detects endogenous levels of total TUSC2 protein. |
| Reconstitution & Storage | PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year. |
| Precautions | TUSC2 / PAP Antibody (aa41-90) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TUSC2 |
|---|---|
| Synonyms | C3orf11, FUS1, LGCC, PDAP2 |
| Function | May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells. |
| Tissue Location | Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.
References
Kondo M.,et al.Oncogene 20:6258-6262(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Uno F.,et al.Cancer Res. 64:2969-2976(2004).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
