|Application ||WB, IHC-P, IF, E|
|Calculated MW||45811 Da|
|Dilution||ELISA (1:10000), IF (1:100 - 1:500), IHC-P (5 µg/ml), WB (1:500 - 1:1000),|
|Other Names||OXER1, GPR170, G-protein coupled receptor 170, HEOAD54, Oxoeicosanoid (OXE) receptor 1, Oxoeicosanoid receptor 1, TG1019|
|Target/Specificity||OXER1 Antibody detects endogenous levels of total OXER1 protein.|
|Reconstitution & Storage||PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.|
|Precautions||OXER1 Antibody (aa212-261) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.
Hosoi T.,et al.J. Biol. Chem. 277:31459-31465(2002).
Jones C.E.,et al.Mol. Pharmacol. 63:471-477(2003).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Takeda S.,et al.FEBS Lett. 520:97-101(2002).
Hillier L.W.,et al.Nature 434:724-731(2005).
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