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TCL / RHOJ Antibody (clone 1D7)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF |
|---|---|
| Primary Accession | Q9H4E5 |
| Other Accession | 57381 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Clone Names | 1D7 |
| Calculated MW | 23821 Da |
| Dilution | IF (1:100), IHC-P (10 µg/ml), WB (1:2000), |
| Gene ID | 57381 |
|---|---|
| Other Names | RHOJ, ARHJ, Ras homolog family member J, TC10-like Rho GTPase, TC10B, RAS-like, family 7, member B, RASL7B, RHOI, Tc10-like GTP-binding protein, TCL |
| Target/Specificity | Human TCL / RHOJ |
| Reconstitution & Storage | PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing. |
| Precautions | TCL / RHOJ Antibody (clone 1D7) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RHOJ |
|---|---|
| Function | Plasma membrane-associated small GTPase specifically involved in angiogenesis (PubMed:21628409, PubMed:24434213, PubMed:30158707). Required for endothelial cell migration during vascular development via its interaction with GLUL (PubMed:30158707). Elicits the formation of F-actin-rich structures, thereby regulating endothelial cell migration (PubMed:30158707). |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side Note=Localization to the plasma membrane is regulated by GLUL |
| Tissue Location | Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology (By similarity).
References
Vignal E.,et al.J. Biol. Chem. 275:36457-36464(2000).
Allen M.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
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