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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HIBCH Antibody (clone 5C5)   

HIBCH Antibody (clone 5C5)

Mouse Monoclonal Antibody

     
  • IHC - HIBCH Antibody (clone 5C5) ALS16720
    Anti-HIBCH antibody IHC staining of human liver.
  • IF - HIBCH Antibody (clone 5C5) ALS16720
    Anti-HIBCH mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently...
  • WB - HIBCH Antibody (clone 5C5) ALS16720
    HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HIBCH...
  • WB - HIBCH Antibody (clone 5C5) ALS16720
    Western blot of extracts (35 ug) from 9 different cell lines by using anti-HIBCH monoclonal...
  • FC - HIBCH Antibody (clone 5C5) ALS16720
    HEK293T cells transfected with either overexpress plasmid (Red) or empty vector control plasmid...
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, Flo
Primary Accession Q6NVY1
Other Accession 26275
Reactivity Human, Rat, Dog
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 5C5
Calculated MW 43482 Da
Dilution Flo (1:100), IF (1:100), IHC-P (10 µg/ml), WB (1:2000),
Additional Information
Gene ID 26275
Other Names HIBCH, HIB-CoA hydrolase, HIBYL-CoA-H, HIBYLCOAH
Target/Specificity Human HIBCH
Reconstitution & Storage PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.
PrecautionsHIBCH Antibody (clone 5C5) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HIBCH
Function Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
Cellular Location Mitochondrion.
Tissue Location Highly expressed in liver and kidney, also detected in heart, muscle and brain (at protein level). Not detected in lung.
Volume 50 µl
Research Areas
Citations (0)

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Background

Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.

References

Hawes J.W.,et al.J. Biol. Chem. 271:26430-26434(1996).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Choudhary C.,et al.Science 325:834-840(2009).

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$ 395.00
Cat# ALS16720
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